Tuesday, June 14, 2011

  • http://medicalxpress.com/news/2011-05-worm-discovery-billion-people-worldwide.html
    http://en.wikipedia.org/wiki/Trichuris_trichiura Light infestations (<100 worms) are frequently asymptomatic. The female T. trichiura produces 2,000–10,000 single celled eggs per day. Within the United States, infection is rare overall but may be common in the rural Southeast where 2.2 million people are thought to be infected.
    Whipworm as a therapeutic agent for IBD and other inflammatory disorders
    Main article: Helminthic therapy
    The hygiene hypothesis suggests that various immunological disorders that have been observed in humans only within the last 100 years, s...uch as Crohn's disease, or that have become more common during that period as hygienic practices have become more widespread, may result from a lack of exposure to parasitic worms (also called helminths) during childhood. The use of Trichuris suis ova (TSO, or pig whipworm eggs) by Weinstock, et al., as a therapy for treating Crohn's disease[8][9][10] and to a lesser extent ulcerative colitis[11] are two examples that support this hypothesis. There is also anecdotal evidence that treatment of inflammatory bowel disease (IBD) with TSO decreases the incidence of asthma,[12] allergy,[13] and other inflammatory disorders.[citation needed] Some scientific evidence suggests that the course of multiple sclerosis may be very favorably altered by helminth infection;[14] TSO is being studied as a treatment for this disease.[15]
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440857/ Anti-inflammatory and anti-arthritic effects of yucca schidigera: A review
    Palytoxin is a huge molecule with chemical formula C129H223N3O54. http://en.wikipedia.org/wiki/Palytoxin
    http://www.oxphos.org/index.php?option=com_content&task=view&id=86&Itemid=1 Succinate in hypoxia
    T8690 Thioredoxin human ≥90% (SDS-PAGE), recombinant, expressed in Escherichia coli (N-terminal hist http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO|BRAND_KEY&N4=T8690|SIGMA&N25=0&QS=ON&F=SPEC
    http://en.wikipedia.org/wiki/Alanine_cycle
    http://groups.google.com/group/alt.baldspot/browse_thread/thread/c3a401892a9be495/c78bfd7536edd801?lnk=gst&q=creatine#c78bfd7536edd801
    The increases in serum alanine transaminase levels (after 3 hours and 12 hours of reperfusion) were significantly (P < .01) attenuated in the BH(4) group. http://www.ncbi.nlm.nih.gov/pubmed/16546503 Cytoprotective function of tetrahydrobiopterin in rat liver ischemia/reperfusion injury.
    Serum aspartame transaminase may be 15 percent higher in black men than white men.
    Plasma homocysteine levels
    were increased in all experimental groups from 6 wk onward and
    were greatest in FDE. Ethanol feeding reduced liver methionine
    synthase activity, S-adenosylmethionine (SAM), and glutathione,
    and elevated plasma malondi...aldehyde (MDA) and alanine
    transaminase. Folate deficiency decreased liver folate levels and
    increased global DNA hypomethylation. Ethanol feeding and folate
    deficiency acted together to decrease the liver SAM S-adenosylhomocysteine
    (SAH) ratio and to increase liver SAH, DNA strand
    breaks, urinary 8-oxo-2 -deoxyguanosine [oxo(8)dG] mg of creatinine,
    plasma homocysteine, and aspartate transaminase by more
    than 8-fold. Liver SAM correlated positively with glutathione,
    which correlated negatively with plasma MDA and urinary
    oxo(8)dG. Liver SAM SAH correlated negatively with DNA strand
    breaks, which correlated with urinary oxo(8)dG. Livers from
    ethanol-fed animals showed increased centrilobular CYP2E1 and
    protein adducts with acetaldehyde and MDA.
    In summary, the present study demonstrates that the addition
    of folate deficiency to a diet containing excessive ethanol both
    enhances abnormal hepatic methionine metabolism and promotes
    the early development of alcoholic liver injury. Feeding...
    the combined FDE diet resulted in the greatest increase in
    plasma Hcy and liver SAH levels and the greatest reduction in
    the SAM SAH ratio (Table 2), together with an 8-fold increase
    in plasma AST.
    Vasopressin receptors control fidelity  http://groups.google.com/group/sci.med.psychobiology/browse_thread/thread/1d878fcd03ff115b/331820b4dda7d3d?q#0331820b4dda7d3d
    http://www.jlaforums.com/viewtopic.php?p=31731514 Endogenous and Exogenous Cannabinoids Modulate Inflammation
    Interferon-y Is a Critical Modulator of CB2 Cannabinoid Receptor Signaling during Neuropathic Pain http://www.jneurosci.org/content/28/46/12136.full.pdf

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